Approach Effectiveness study (WP1)

Primary objective

1. To estimate the effect of PoC VL monitoring on viral load suppression among children and adolescents living with HIV in East Africa at 6 and 12 months of follow-up.

Secondary objectives

1. To describe the effect of PoC VL monitoring on the proportion of children and adolescents living with HIV that experiences virological rebound after initial suppression within 6 and 12 months of follow-up.
2. To describe the effect of PoC VL monitoring on time to initiation of intensive adherence counselling following virological failure among children and adolescents living with HIV.
3. To estimate the effect of PoC VL monitoring on the proportion of children and adolescents living with HIV that experiences change of ART regimen within 6 and 12 months of follow-up.
4. To determine the effect of PoC VL monitoring on the proportion of children and adolescents living with HIV that is retained in care at 6 and 12 months.