To strengthen collaboration and optimize the use of shared research infrastructures, capacity building resources and opportunities, so that partner institutions across the region can conduct high quality clinical research together.

To increase the number and retention of independent African researchers, research leaders and managers, by creating opportunities for them to grow, lead studies and build lasting careers in the region.

To boost and deliver an Eastern Africa training and mentorship program that equips early career and established researchers with the skills needed to design, conduct and manage high quality clinical studies.

To establish new work packages (NID) that manage and set up the facilities needed to conduct clinical trials on the neglected, emerging and re-emerging diseases that burden the region.

To strengthen and strategically expand South-South and North-South collaborations between researchers and institutions, with a focus on helping less established institutions build capacity for high quality clinical research across the region.

To promote networking and dialogue between researchers, communities and policy makers, so that health research evidence is used for shared knowledge management, policy change and better health programming in Eastern Africa.