Researchers in Uganda have made significant strides in vaccine development using a novel adenovector backbone that was previously developed during the COVID-19 pandemic, using funds from the government of Uganda. The developed backbone is an open system that can be used in the development of other vaccines for infectious diseases. Notably, the platform is adaptable for both animal and human testing and is currently being utilized by a consortium of researchers led by the Uganda Virus Research Institute and the MRC/UVRI and LSHTM Uganda Research Unit.